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Optimizing Post-Operative Pain Management

There are 4 central tenets to optimizing post-operative analgesia: (1) provide preemptive analgesia, (2) use multi-modal pain management, (3) deliver overlapping/continuous analgesia, and (4) match the analgesic plan to the severity of surgical pain.4 In order to follow these guidelines, veterinarians must consider methods of minimizing the transduction and transmission of pain in peripheral tissue, attenuating modulation of pain in the spinal cord, and reducing the conscious perception of pain. The use of analgesics with complementary modes of action can be employed to target these various points along the pain pathway (Table 2).

There is a clear unmet need for a long-acting local anesthetic that can be added to the multi-modal analgesic arsenal to provide pain management for veterinary patients for extended periods.

Post-Operative Pain Management Video

Please note charts are best viewed on a larger screen or desktop.

3. Epstein ME, Rodanm I, Griffenhagen G, et al. 2015 AAHA/AAFP pain management guidelines for dogs and cats. J Feline Med Surg. 2015;17(3):251-272.

4. Mathews K. Kronen PW, Lascelles D, et al. Guidelines for recognition, ossessment and treatment of pain. J Small Ani. 2014;55(6):E10-E68.

11. KuKanich B. Pharmacokinetics of acetaminophen, codeine, and the codeine metabolites morphine and codeine-6-glucoronide in healthy greyhound dogs. J Vet Pharmacol Ther. 2010;33(1):15-21.

12. KuKanich B, Spade J. Pharmacokinetics of hydrocodone and hydromorphone after oral hydrocodone in healthy greyhound dogs. Vet J. 2013;196(2):266-268.

13. Recuvyra® [package insert]. Indianapolis, IN: Elanco Animal Health; 2014.