NOCITA is a single dose administered by tissue infiltration injection during surgical closure into the tissues to control post-operative pain in cranial cruciate ligament (CCL) surgery in dogs. The pharmacokinetic characterization associated with bupivacaine after subcutaneous NOCITA® (bupivacaine liposome injectable suspension) or bupivacaine HCl solution was administered to beagle dogs is provided in Table 3.21
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21. NOCITA® [package insert]. Leawood, KS: Aratana Therapeutics, Inc.; 2016.